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產(chǎn)品中心抗體Polyclonal AntibodyK101524PAnti-TIMP1 Polyclonal Antibody
產(chǎn)品型號：K101524P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：1054
010-50973130
產(chǎn)品分類
Anti-TIMP1 Polyclonal Antibody
| 英文名稱 | Anti-TIMP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | ABH;ABH1;ALKBH;alkB;hABH |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應(yīng) | Human |
| 蛋白分子量 | 33kDa |
| Gene ID | 7076 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human TIMP1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human TIMP1 |
| Subcellular Locations | Secreted |
| Swiss Prot | P01033 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. |
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